Functional connectivity and responses to chemoreceptor stimulation of medullary ventrolateral respiratory column neurons
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Functional connectivity and responses to chemoreceptor stimulation of medullary ventrolateral respiratory column neurons" (2010). Graduate Theses and Dissertations. love and encouragement have successfully guided me along life's path. ACKNOWLEDGEMENTS I would like to express my deepest gratitude to my mentors, Dr. their patience and support in the completion of this research. I am extremely grateful to all the staff and faculty of the Department of Pharmacology and Physiology and the Graduate and Postdoctoral Affairs office for being part of my support structure. I am indebted to all the members of the for their tireless efforts. This work would not have been possible without the unrelenting support and encouragement of my parents, family and friends. The original of this document contains color that is necessary for understanding the data. The original dissertation is on file with the USF library in Tampa, Florida.
منابع مشابه
Tonic and reflex control of the cardio-respiratory system by neurons in the ventral medulla
To investigate the channels and neurotransmitters in the ventrolateral medulla (VLM) oblongata that are responsible for the maintenance of sympathetic tone and cardio-respiratory reflex regulation. Microinjections of excitant amino acid (glutamate, 100 nl, 100 mM), calcium channel blockers, agonists and antagonists were made throughout the VLM in anaesthetized rats. Arterial blood pressure, sym...
متن کاملTonic and reflex control of the cardio-respiratory system by neurons in the ventral medulla
To investigate the channels and neurotransmitters in the ventrolateral medulla (VLM) oblongata that are responsible for the maintenance of sympathetic tone and cardio-respiratory reflex regulation. Microinjections of excitant amino acid (glutamate, 100 nl, 100 mM), calcium channel blockers, agonists and antagonists were made throughout the VLM in anaesthetized rats. Arterial blood pressure, sym...
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The medullary ventral respiratory column (VRC) of neurons is essential for respiratory motor pattern generation; however, the functional connections among these cells are not well understood. A rostral extension of the VRC, including the retrotrapezoid nucleus/parafacial region (RTN-pF), contains neurons responsive to local perturbations of CO(2)/pH. We addressed the hypothesis that both local ...
متن کاملCentral and peripheral chemoreceptors evoke distinct responses in simultaneously recorded neurons of the raphé-pontomedullary respiratory network.
The brainstem network for generating and modulating the respiratory motor pattern includes neurons of the medullary ventrolateral respiratory column (VRC), dorsolateral pons (PRG) and raphé nuclei. Midline raphé neurons are proposed to be elements of a distributed brainstem system of central chemoreceptors, as well as modulators of central chemoreceptors at other sites, including the retrotrape...
متن کاملCentral chemoreceptor modulation of breathing via multipath tuning in medullary ventrolateral respiratory column circuits.
Ventrolateral respiratory column (VRC) circuits that modulate breathing in response to changes in central chemoreceptor drive are incompletely understood. We employed multielectrode arrays and spike train correlation methods to test predictions of the hypothesis that pre-Bötzinger complex (pre-BötC) and retrotrapezoid nucleus/parafacial (RTN-pF) circuits cooperate in chemoreceptor-evoked tuning...
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تاریخ انتشار 2015